Physiological methods in developmental research
Loeb received his medical degree at Strasbourg in 1884 and worked at institutions in Europe and the United States. Research at Chicago and Berkeley was accompanied by work at marine stations. In 1910 he joined the Rockefeller Institute for Medical Research.
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Treating unfertilized eggs
In 1899 Loeb reported that particular inorganic solutions could initiate development of unfertilized sea-urchin eggs into larvae. The experiments tested conditions for activating an already living egg; they did not create living organisms from nonliving material.
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Controlling experimental conditions
Loeb sought explanations by manipulating physical and chemical conditions. His investigations also included animal tropisms and protein chemistry. Artificial Parthenogenesis and Fertilization, published in 1913, brought together work comparing treatments, reproducibility and developmental outcomes.
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