Physiology and pharmacology
Dale studied natural sciences and medicine at Cambridge and undertook research in London and in Ehrlich’s Frankfurt laboratory. Joining the Wellcome Physiological Research Laboratories in 1904, he investigated ergot extracts and the actions of biologically active substances.
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Acetylcholine and transmission
Dale’s investigations of acetylcholine’s effects on organs helped explain how some nerve signals act through chemical substances. His pharmacological research complemented Loewi’s nerve-stimulation experiments. The two shared the 1936 Nobel Prize for discoveries relating to chemical transmission of nerve impulses.
Research institutions
Dale later directed Britain’s National Institute for Medical Research and participated in Wellcome Trust research funding. He served as President of the Royal Society from 1940 to 1945, linking experimental pharmacology with public research institutions and charitable support for science.
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